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CBD Oil 101

Cannabidiol (CBD), is one of more than 100 known components found in hemp called cannabinoids. There’s an ever-increasing amount of research pointing to various health benefits in CBD, all while being non-psychoactive and legal in all 50 states and in countries around the world.

Pre-clinical trials, research, and other various studies are showing CBD can be anti-convulsive, anti-psychotic, anti-nausea, and anti-inflammatory and may have neuroprotective properties as well.

CBD oil or Cannabidiol oil is derived from the Cannabis Sativa plant, specifically the hemp variety. This is the first distinction to make when learning about CBD oil, the fact it is derived from hemp and not marijuana means it is non-intoxicating or non-psychoactive like marijuana is.

Hemp vs Marijuana

Hemp and marijuana are different varieties of the Cannabis genus of plants, bred for different purposes.

Industrial hemp is exclusively produced by Cannabis sativa, while marijuana can refer to the sub-genuses of Cannabis sativa, Cannabis indica, or Cannabis ruderalis. Industrial hemp is grown to be fibrous and durable, with very long stalks and as few flowering buds as possible.

Marijuana strains of cannabis are typically smaller, flimsier, and have as many flowering buds as their breeding can allow.

Marijuana is bred with the sole purpose of maximizing the concentration of THC, while industrial hemp naturally has trace amounts of THC and fairly high amounts of CBD.

Hemp’s chemical profile means you can’t get “high” from it. For centuries it has been used to create medicinal remedies, food, and oil, as well as other products including rope, bricks, natural polymers, fiber, clothes, and many more.

Marijuana is used recreationally and medicinally only.

CBD Oil vs. THC

Chemically CBD and THC are both cannabinoid compounds. Their plants as well as down to the molecules they look similar but are very different. There are over 100 known cannabinoids. THC and CBD are the two most common, and therefore the most studied. THC is a psychoactive compound, whereas CBD is non-psychoactive.

CBD oil contains no more than a trace of THC, or .3% by law, which is far too small an amount to make anyone high.

About CBD Oil, Cannabidiol CBD Oil Benefits, CBD Oil effects
Cannabinoids CBD Benefits Chart List

More About CBD Oil

The U.S. Food & Drug Administration, the World Health Organization and numerous private and government laboratories are constantly researching current and future uses of CBD oil.

The FDA is collecting public comments and its deputy commissioner, Anna K. Abram, has said, “CBD has been shown to be beneficial in experimental models of several neurological disorders, including those of seizure and epilepsy.”

Medical News Today cited many promising research findings and urged more investigation to determine the full scope of CBD’s efficacy.

Research on cannabidiol has found few or no negative side effects, according to Medical News Today, a leading health publication.

“This means CBD oil may be a good option for people who do not tolerate the side effects of other medications for anxiety, including addiction.”

CBD Oil Effects

How does CBD Oil work? You don’t have to be a scientist to understand how CBD oil affects the human body, but it helps. Fortunately, we can refer to the work of scientists who do understand the benefits of CBDs. Here are some findings:

As active chemical compounds, cannabinoids act on cannabinoid receptors that are part of our endocannabinoid system (commonly called the ECS). This system includes two endocannabinoid receptors. CB1 is located in the central nervous system and CB2 is in the peripheral nervous system. The compounds affect the release of neurotransmitters in the brain.

cbd oil effects chart
CBD Oil Effects Chart

What Is The Endocannabinoid System?

The ECS may be the most important physiologic system involved in establishing and maintaining human health. Endocannabinoids and their receptors are found throughout the body – in the brain, organs, connective tissues, glands, and immune cells. In each tissue, the cannabinoid system performs different tasks, but the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment.

Endocannabinoids and cannabinoids are also found at the intersection of the body’s various systems, allowing communication and coordination between different cell types.

What Are Endocannabinoids?

Endocannabinoids are chemical messengers that play a role in sleep, appetite, mood, pain, pleasure, memory and many other functions. They signal your body when to begin these processes and when to stop them – all in an effort to keep a proper balance in your system.

Endocannabinoids are the substances our bodies naturally make to stimulate these receptors. The two most well understood of these molecules are called anandamide and 2-arachidonoylglycerol (2-AG). They are synthesized on-demand from cell membrane arachidonic acid derivatives, have a local effect, and short half-life before being degraded by the enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).

CB1 Receptors

The CB1 receptors are primarily located on nerve cells in the brain, spinal cord, but they are also found in some peripheral organs and tissues such as the spleen, white blood cells, endocrine gland and parts of the reproductive, gastrointestinal and urinary tracts.

In the brain, the CB1 receptors are abundant in the cerebellum, basal ganglia, hippocampus and dorsal primary afferent spinal cord regions, which is why cannabinoids influence functions such as memory processing, pain regulation and motor control. In the brain stem, the concentration of cannabinoids is low, which may be related to why cannabis use is not associated with sudden death due to depressed respiration, for example.

CB2 Receptors

The CB2 receptors are mainly found on white blood cells, in the tonsils and in the spleen. The immune cells also express CB1, although there are fewer of them than CB2. In the immune system, one important function of the cannabinoid receptors is the regulation of cytokine release. Selective CB2 receptor agonists have become increasingly popular for their anti-inflammatory and anti-cancer effects.

What Are Phytocannabinoids?

Phytocannabinoids or cannabinoids for short, are plant substances that stimulate cannabinoid receptors. Most phytocannabinoids have been extracted from cannabis sativa, cannabinoids such as cannabidiol (CBD) and cannabinol (CBN) as well as others.

CBD Oil Effects & Benefits – Science Stuff

Ok, this is technical, apologies.

CBD indirectly stimulates endogenous cannabinoid signaling by suppressing the enzyme fatty acid amide hydroxylase (FAAH) – the enzyme that breaks down anandamide.

Cannabinoid molecules found in cannabis plants are considered “exogenous ligands” to the cannabinoid (CB) receptor family, anandamide is an “endogenous” cannabinoid ligand – meaning it binds to one or more cannabinoid receptors and is found naturally inside the body. Anandamide favors the CB1 receptor, which for us is concentrated in the brain and central nervous system. Because FAAH is responsible for breaking down anandamide, less FAAH remains present in the body for a longer duration. More anandamide means greater CB1 activation.

By inhibiting the enzyme that metabolizes and destroys anandamide, CBD boosts the body’s protective endocannabinoid response. CBD also stimulates the release of 2-AG, another endocannabinoid that activates both CB1 and CB2 receptors – CB2 receptors are predominant in the peripheral nervous systems and the immune system.

Vanilloid Receptor

Cannabidiol has been shown to directly interact with other, so called “G-protein-coupled” receptors to confer its medicinal effect. CBD, for example, binds to the TRPV-1 receptor, which is known to mediate pain perception, inflammation and body temperature.

TRPV is the technical abbreviation for “transient receptor potential cation channel subfamily V.” Scientists also refer to it as the “vanilloid receptor,” named after the flavorful vanilla bean.

CBD is a TRPV-1 “agonist” or stimulant. This is likely one of the reasons why CBD rich oil may be a particularly effective treatment for neuropathic pain.

Adenosine Receptor

CBD has it’s anti-anxiety effect by activating the adenosine receptors. Adenosine receptors play significant roles in cardiovascular function, regulating myocardial oxygen consumption and coronary blood flow. The adenosine (A2A) receptor has broad anti-inflammatory effects throughout the body.

Adenosine receptors also play a significant role in the brain. They down-regulate the release of other neurotransmitters such as dopamine and glutamate.

Serotonin Receptor

At high concentrations, CBD directly activates the 5-HT1A (hydroxytryptamine) serotonin receptor, thereby conferring an anti-depressant effect. This receptor is implicated in a range of biological and neurological processes, including but not necessarily limited to, anxiety, addiction, appetite, sleep, pain perception, nausea and vomiting.

What About CBD Side Effects?

Researchers have conducted many small studies about CBD’s safety and found most people have no serious side effects. This includes the central nervous system, mood and vital signs.

Fatigue is the most common side effect; others are diarrhea and changes in appetite or weight.

Whenever a person is considering a new treatment, he or she should consult a qualified healthcare practitioner.

To see the latest research & studies about CBD Oil, visit

CBD is not addictive

Nora Volkow, director of the National Institute on Drug Abuse, sees much value in CBD and urges more exploration of its potential health uses.

“In short, CBD appears to be safe with no addictive effects, and the preliminary data suggest that it may have therapeutic value for a number of medical conditions,” she wrote in an article for the Huffington Post.

This is the leader of a national drug abuse center saying CBD is safe!

What’s the best method of taking Cannabidiol CBD Oil?

There are many methods to take CBD. Some people prefer to ingest it orally as a tincture under the tongue. Each method has a different level of absorption and everyone’s body is different. When you process anything through the liver, less of it gets into your bloodstream. Inhaling or vaping it is a more direct route and thus effects are noticed sooner, whereas edible CBD products will take longer to notice effects from. Always consult with your doctor or naturopath before deciding what is best for you.

Can I add CBD oil to my food rather than taking sublingually if I don’t like the taste?

We recommend letting the oil absorb into your mouth, preferably under the tongue rather than swallowing it right away. To help with the taste, look to try a flavored CBD tincture, or have a glass of orange juice, apple juice or cider ready to chase your CBD oil down AFTER it has been under your tongue for a minute or so. CBD oil is not water-soluble, so it won’t mix with water or juice first. Use the water or juice after like you would a chaser.

Cannabidiol CBD Oil Dose Instructions – Serving sizes

Each of our bodies are unique and different, there’s only one of you. The recommended serving size is usually enough for most people to feel relief, but some take 2-3 times that amount or more. CBD oil’s efficacy does not seem to be dictated by age, gender, weight, nor nationality.

This means all products come with a starting recommended serving size but that does not mean it will be what your ECS needs (Endocannabinoid System). We all have our “sweet spot” or therapeutic serving size, we just need to experiment to find it.

The exact properties of CBD are still being researched and the ideal serving size for particular conditions hasn’t been discovered yet, but we look forward to it.

Because CBD has few side effects, taking “too much” CBD will not hurt you, but you should still exercise moderation and use common sense.

How long do I need to take Cannabidiol CBD Oil?

That may vary from person to person.

Many people find that they can gradually start reducing the amount of CBD needed after they’ve built it up in their system. We recommend you take at least a couple milligrams daily, but that’s completely your choice and dependent on your goals.

How quickly does Cannabidiol CBD Oil work?

Everyone is different, and there is really no uniform result.

It make take some people a few days to a week before seeing results or feeling any effect, while others may feel immediate results. In addition, some people do not feel anything from taking the products while others say they can feel a very subtle calming effect. Results will vary just as they do with any natural supplement, herbal, botanical, or traditional medicine.

Is there THC in your Cannabidiol CBD Oil products?

Most of our products contain very little THC, if any. The legal maximum is less than 0.3 percent. We do have CBD oil that is 100% THC free.

Will I fail a drug test if I take Cannabidiol CBD Oil?

We cannot guarantee any specific results for a drug test. There is no more than a trace amount of THC in our products, but the compound may still be present when you are tested. Also, some drug tests may search for all cannabinoids, including CBD, which is active in our products.

Who can take Cannabidiol CBD Oil?

Because this is a food-based product, there is no restriction on who can take this unless there are other concerns, medications or other health-related reasons. We always recommend you consult with a medical professional.

Is Cannabidiol CBD Oil a drug?

No. All of our hemp products are considered food or supplements.

Can I drive after taking Cannabidiol CBD Oil?

There’s no necessary warning against driving, but CBD may make you feel tired if you take a large amount. We recommend learning how your body reacts to CBD first.

CBD Oil Research Links

As users ourselves, we constantly read and talk with researchers and customers to understand more about Cannabidiol CBD Oil.

We will gladly direct you to relevant studies through an email request.

Or if you’d like to do your own research, we recommend websites such as PubMed, which is The US National Library of Medicine National Institutes of Health website.

*These statements have not been evaluated by the FDA and are not intended to diagnose, treat or cure any disease. Always check with your physician before starting a new dietary supplement program.

In addition to the above disclaimer, it is interesting to note: The United States Government has a patent on Cannabibiol.



About Cannabidiol – Which CBD Product Is Right For Me?

Our CBD Oil Buyer’s Guide can help! As you shop around for CBD-rich hemp oil, you may notice a discrepancy in pricing between products that appear to be pretty much the same thing. This guide will discuss the differences among various types of products and clearly lay out your options, including the generic things to look for.

What to Look for in CBD Products

You want to know about CBD oil brands, strength, plant source, and more. . .

The amount of CBD in a product may range from 3mg to 2,000mg+. These are dietary supplements, so there is no set dosage that’s guaranteed to be optimal for everyone. A mix of research and trail/error is a necessary part of finding the right amount for your individual needs.

Additionally, compare the CBD amount to the total volume of product. For instance, you may see two vape oils with 50mg of CBD; one is in a 10ml bottle and the other a 5ml bottle. The 5ml bottle won’t last as long as the 10ml, however each puff off your vaporizer will have more CBD than it would with the 10ml, because it’s more concentrated (less “filler”). Also consider, a 5ml with 50mg of CBD is the same exact concentration as a 10ml with 100mg of CBD.

Method of intake If you’re going to invest in a CBD supplement, make sure you understand how to take the product and if that method is right for you. While lotions and balms may be worth trying for certain visible skin issues, they may not be right for assisting something sub-dermal. Below you’ll see information about several types of supplements.

Other ingredients (i.e. terpenes)CBD may not be the only important thing to look for in your supplement. Although CBD is a hot topic right now, research suggests it be more beneficial with the so-called “entourage effect” when mixed with terpenes. Terpenes are organic hydrocarbons found in the essential oils of plants. However understudied, researchers have recently suggested that they may possess anti-inflammatory properties. Terpenes are responsible for the varying, unique smells experienced with cannabis. The most common terpenes include limonene, myrcene, alpha-pinene, linalool, among others.

Don’t give up if one product doesn’t seem to work for you, consider trying a higher concentration in another form. With a growing market, unfortunately, and inevitably comes the snake oil. As a constant tester of new products, we’re frustrated by the amount of incorrectly labeled products.

About CBD Oil Product Types

From Farm to You

The products available at New Life Hemp Oil are made from CBD rich strains of Cannabis Sativa hemp plants. Many of our products are made from US, organically grown plants from Colorado or Kentucky. While other products are made from European plants with high Cannabidiol (CBD) content, extracted and packaged in Michigan.

NLHO products and extracts offered are derived from the hemp plant and not marijuana, and can also be referred to as; hemp oil, CBD-rich hemp oil, hemp-derived CBD oil, CBD-rich cannabis oil, or plainly “hemp extracts,”  as most products contain more cannabinoids than just CBD.

1. Hemp CBD Oil Drops/Tincture

100mg ~ 1500mg CBD Hemp oil drops, such as Tasty Drops or Charlotte’s Web Hemp Oil, are dietary supplements in a liquid form. This type of product will come in a sub-lingual tincture. In layman’s term, that just means a glass bottle with contents meant explicitly for oral use. This oil is placed under the tongue (hence the “sub-lingual” part), held in the mouth for a certain period of time, and then swallowed. During your shopping experience, you’ll notice sometimes these will come in a bottle with a dropper top, and other times with a sprayer top. The spray tops are considered quicker, and the dropper more accurate. Neither is necessarily better than the other, this is purely personal preference.

Hemp oil drops are great for those who do not wish to smoke or vape. While there are more potent forms of hemp oil supplements (see “Hemp Oil Tubes”), those are not flavored like the drops are. While there will always be a slight hempy taste, with the exception of some vapes, the drops are normally available in an assortment of flavors. Personally, we believe cinnamon and peppermint flavors do the best at masking that earthy tone, but of course don’t touch them if you dislike these flavors (they’re strong). Other flavor options range from vanilla to berry.

CBD oil tincture drops, how to dose CBD oil
How To Take CBD Oil Drops

2. CBD Oil Pure Concentrated Extracts

At 15% ~ 50% CBD content, the highest concentrations of CBD in hemp oil supplements are normally found in tubes, or oral syringes. It comes in either a paste or gel substance and ranges in color from dark green/black to bright orange. Just like the drops, this type of supplement goes under the tongue, where it’s suggest you hold it for about 90 seconds before swallowing to let the oil absorb into your body. Because this type of supplement is so strong, you can take just a small amount instead of several dropper fills from a liquid tincture. Dosage is completely up to you based off recommendations from your doctor and what you’ve learned through your own testing.

You’ll notice the CBD in this product is measured in percentage. Don’t let this confuse you, it can easily be converted into milligrams. For example, 15% means there is 150mg of CBD per gram. So multiply the amount of grams by 150 to find the total amount of CBD. If we do this, we’ll find a 10 gram tube with 15% CBD has 1,500mg of CBD.

CBD Pure Concentrated Extracts

When the oil is extracted from the hemp plant and does not go through any other processes, we get the Raw Green version.

Moving forward, the oil is heated in a lab to extract CO2; a process known as decarboxylation. This “activates” all the acid version of the cannabinoids. We now have the Blue version.

The final step is filtering the oil. This removes most of the extra plant parts and turns the thick, dark paste into an orange-tinted gel substance. The oil will now have a higher concentration by volume, but may contain fewer phytonutrients than the unfiltered versions. This is the Gold version. CBD extract concentrates are the best way to achieve the best CBD oil effects.

CBD oil extract concentrates
RAW CBD Extract

3. CBD Oil Capsules & Softgels – Pills

On the go ? New Life Hemp Oil capsules pill products are great and easy to use ! With superior, well know brands of Hemp CBD Oil to choose from, you can’t go wrong. Endoca, Entourage and Tasty Hemp Oil capsules are the best in the industry. Pick your mg strength, quantity and brand of choice. Start feeling better no matter where you are, with medicinal grade CBD Oil capsules or softgels.

CBDfx Capsules 750mg CBD, 30 Ct, 25mg ea

4. Hemp Oil Topicals – CBD Oil Lotions & Balms

CBD has extensively proven its effectiveness in treating numerous skin diseases, disorders, and muscle and joint pain. To fully take advantage of these beneficial properties, CBD oil is now available in user-friendly balms and lotions.

CBD-rich hemp cream can relieve mild pain and reduce itching at the same time as your skin is nourished and hydrated resulting in a healthy, smooth and even surface. The healing and soothing ointment may also reduce swelling, inflammation, and help burns to heal faster.

10mg ~ 50mg CBD There are several CBD-infused topicals available on the market such as salves and lotions.

5. CBD Oil Edibles

Edibles are an easy and enjoyable way of taking CBD. Our Tasty Hemp Oil Gummies taste fantastic and each CBD gummy contains 25mg of CBD and is a full spectrum treat.

CBD – History of Hemp

Hemp has been popular for thousands of years. Historians date its use back thousands of years, when people began finding it helpful in food, herbs and other products. And National Geographic Magazine unearthed the account of a British physician who published an article in 1843 – more than 150 years ago! – reporting that cannabis oil had stopped an infant’s frequent convulsions.

Research in hemp was relatively light for many years, partly because hemp was caught in the crossfire of America’s “War on Drugs.” Now, however, as government and business leaders learn to distinguish between CBDs and marijuana, more scientists are focusing their research on CBD and other cannabinoids.

Helped by modern technology, many foresee CBD hemp oil playing an even bigger part in medicine and personal health care for many years to come.

We hope you have learned more about CBD oil and feel confident in trying one of our incredible CBD products.

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